259870-32-1
259870-32-1
Chemical Structure
TGFβ-IN-5
- CAS No.: 259870-32-1
- Formula:C20H16N4
- Molecular Weight:312.37
InChIKey: PJZIQCMPDKJSKB-UHFFFAOYSA-N
SMILES: C1(C2=CC=CC=C2)=NC(NCC3=CC=NC=C3)=C4C=CC=CC4=N1
Biological Activity: TGFβ-IN-5 is a type I transforming growth factor-β receptor (TGF-β R1) kinase inhibitor with an IC50 value of 0.0485 μM. TGFβ-IN-5 reverses the effect of TGF-β-mediated cell activation on the expression of fibrosis-related genes. TGFβ-IN-5 can be used in the research of fibroproliferative diseases[1].
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TGFβ-IN-5 | 98.03% | TGFβ-IN-5 is a type I transforming growth factor-β receptor (TGF-β R1) kinase inhibitor with an IC50 value of 0.0485 μM. TGFβ-IN-5 reverses the effect of TGF-β-mediated cell activation on the expression of fibrosis-related genes. TGFβ-IN-5 can be used in the research of fibroproliferative diseases. | ||||||||||||||||||||
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References
Keywords
