2601571-19-9
Chemical Structure
ATR-IN-5
- CAS No.: 2601571-19-9
- Formula:C27H32F3N9O
- Molecular Weight:555.60
IUPAC Name: (R)-N-methyl-1-(4-(3-methyl-1-(piperidin-4-yl)-5-(trifluoromethyl)-1H-pyrazol-4-yl)-6-(3-methylmorpholino)pyrimidin-2-yl)-1H-benzo[d]imidazol-2-amine
InChIKey: ZSJYYMBWUZDZSE-MRXNPFEDSA-N
SMILES: CNC1=NC2=CC=CC=C2N1C3=NC(N4[C@@H](COCC4)C)=CC(C5=C(N(C6CCNCC6)N=C5C)C(F)(F)F)=N3
Biological Activity: ATR-IN-5 is a potent inhibitor of ATR. ATR is a class of protein kinases involved in genome stability and DNA damage repair, and is a member of the PIKK family. ATR-IN-5 has the potential for the research of ATR kinase-mediated diseases such as proliferative diseases and cancer (extracted from patent CN112047938A, compound D24)[1].
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ATR-IN-5 | ATR-IN-5 is a potent inhibitor of ATR. ATR is a class of protein kinases involved in genome stability and DNA damage repair, and is a member of the PIKK family. ATR-IN-5 has the potential for the research of ATR kinase-mediated diseases such as proliferative diseases and cancer (extracted from patent CN112047938A, compound D24). | |||||||||||||||||||||
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