2654081-27-1
2654081-27-1
Chemical Structure
(S)-Bleximenib
Synonym(s): (S)-JNJ-75276617;(S)-Menin-MLL inhibitor 24
- CAS 番号: 2654081-27-1
- Formula:C32H50FN7O3
- Molecular Weight:599.78
InChIKey: PDUGAXSIWNMIBQ-MHZLTWQESA-N
SMILES: COCCN(C)CCC[C@H](N1CC2(C1)CN(C3=NC=NN=C3OC4=C(C=C(C=C4)F)C(N(CC)C(C)C)=O)CC2)C(C)C
Biological Activity: (S)-Bleximenib (Compound 28) ((S)-JNJ-75276617) is an isoform of Bleximenib (HY-148669). (S)-Bleximenib shows an IC50 greater than 1 μM in the MEIS1 mRNA expression assay. (S)-Bleximenib can be used in the research of acute myeloid leukemia[1].
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(S)-Bleximenib | 96.06% | (S)-Bleximenib (Compound 28) ((S)-JNJ-75276617) is an isoform of Bleximenib (HY-148669). (S)-Bleximenib shows an IC50 greater than 1 μM in the MEIS1 mRNA expression assay. (S)-Bleximenib can be used in the research of acute myeloid leukemia. | ||||||||||||||||||||
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References
Keywords
