267402-71-1
Chemical Structure
Myoseverin
- CAS No.: 267402-71-1
- Formula:C24H28N6O2
- Molecular Weight:432.52
IUPAC Name: 9-isopropyl-N2,N6-bis(4-methoxybenzyl)-9H-purine-2,6-diamine
InChIKey: IDCOTQWQVPRTNK-UHFFFAOYSA-N
SMILES: CC(N1C=NC2=C(NCC3=CC=C(OC)C=C3)N=C(NCC4=CC=C(OC)C=C4)N=C12)C
Biological Activity: Myoseverin is a microtubule-binding molecule and angiogenesis inhibitor. Myoseverin can induce the reversible fission of multinucleated myotubes into mononucleated fragments. In addition, Myoseverin exerts anti-angiogenic effects by inhibiting endothelial cell function and endothelial progenitor cell differentiation[1][2].
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Myoseverin | 99.17% | Myoseverin is a microtubule-binding molecule and angiogenesis inhibitor. Myoseverin can induce the reversible fission of multinucleated myotubes into mononucleated fragments. In addition, Myoseverin exerts anti-angiogenic effects by inhibiting endothelial cell function and endothelial progenitor cell differentiation. | ||||||||||||||||||||
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- [1]. Rosania GR, et al. Myoseverin, a microtubule-binding molecule with novel cellular effects. Nat Biotechnol. 2000;18(3):304-308. [Content Brief]
- [2]. Park HE, et al. Myoseverin is a potential angiogenesis inhibitor by inhibiting endothelial cell function and endothelial progenitor cell differentiation. DNA Cell Biol. 2006 Sep;25(9):514-22. [Content Brief]
Keywords
