2684252-55-7
Chemical Structure
RET-IN-12
- CAS No.: 2684252-55-7
- Formula:C30H30F3N5O4
- Molecular Weight:581.59
IUPAC Name: 3-(2-(6-(6,7-dimethoxyquinolin-3-yl)pyridin-3-yl)acetamido)-N-(2-(dimethylamino)ethyl)-5-(trifluoromethyl)benzamide
InChIKey: QKFNPAFXWLCCMF-UHFFFAOYSA-N
SMILES: O=C(C1=CC(NC(CC2=CC=C(C3=CN=C4C=C(C(OC)=CC4=C3)OC)N=C2)=O)=CC(C(F)(F)F)=C1)NCCN(C)C
Biological Activity: RET-IN-12 (compound 2) is a RET inhibitor, with IC50 values of 0.3 nM and 1 nM for RET(WT) and RET(V804M), respectively[1].
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RET-IN-12 | RET-IN-12 (compound 2) is a RET inhibitor, with IC50 values of 0.3 nM and 1 nM for RET(WT) and RET(V804M), respectively. | |||||||||||||||||||||
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Keywords