2706637-12-7
Chemical Structure
(7R)-Elisrasib
Synonym(s): (7R)-D3S-001
- CAS. Nr.: 2706637-12-7
- Formula:C32H35F6N7O3
- Molecular Weight:679.66
IUPAC Name: 2-((S)-4-((R)-7-(3-amino-2-fluoro-5-methyl-6-(trifluoromethyl)phenyl)-2-(((2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methoxy)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl)-1-(2-fluoroacryloyl)piperazin-2-yl)acetonitrile
InChIKey: JOLORSRKBHXPFT-KIQNBNRRSA-N
SMILES: FC(F)(F)C(C(C)=CC(N)=C1F)=C1[C@H]2CC3=NC(OC[C@@]45N(CCC5)C[C@@H](C4)F)=NC(N6C[C@@H](N(CC6)C(C(F)=C)=O)CC#N)=C3CO2
Biological Activity: KRASG12C IN-2 (compound 17) is an orally active KRASG12C inhibitor. KRASG12C IN-2 inhibits tumor growth in mice[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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(7R)-Elisrasib | 99.52% | KRASG12C IN-2 (compound 17) is an orally active KRASG12C inhibitor. KRASG12C IN-2 inhibits tumor growth in mice. | ||||||||||||||||||||
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Keywords
