2722645-10-3
Chemical Structure
DNA-PK-IN-4
- CAS No.: 2722645-10-3
- Formula:C20H24N6O3
- Molecular Weight:396.44
IUPAC Name: N,3-dimethyl-4-((7-methyl-8-oxo-9-(tetrahydro-2H-pyran-4-yl)-8,9-dihydro-7H-purin-2-yl)amino)benzamide
InChIKey: BCSHVPZTSJQGJB-UHFFFAOYSA-N
SMILES: O=C(NC)C1=CC=C(NC2=NC=C3N(C)C(N(C4CCOCC4)C3=N2)=O)C(C)=C1
Biological Activity: DNA-PK-IN-4 is a potent inhibitor of DNA-PK. DNA-PK-IN-4 is a imidazolinone derivative compound. DNA-PK-IN-4 inhibits DNA-PKcs activity, thus greatly reducing tumor DNA repair and inducing cells to enter the apoptotic program. DNA-PK-IN-4 has the potential for the research of cancer disease (extracted from patent WO2021209055A1, compound 27)[1].
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DNA-PK-IN-4 | DNA-PK-IN-4 is a potent inhibitor of DNA-PK. DNA-PK-IN-4 is a imidazolinone derivative compound. DNA-PK-IN-4 inhibits DNA-PKcs activity, thus greatly reducing tumor DNA repair and inducing cells to enter the apoptotic program. DNA-PK-IN-4 has the potential for the research of cancer disease (extracted from patent WO2021209055A1, compound 27). | |||||||||||||||||||||
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