2725056-38-0
2725056-38-0
Chemical Structure
ALK5-IN-79
- CAS No.: 2725056-38-0
- Formula:C23H27N7O
- Molecular Weight:417.51
InChIKey: HCGVOSYLBCMBNI-UHFFFAOYSA-N
SMILES: O=C(C)N1CCC(CC1)CCN2N=C(C3=C2N=CN=C3N)C4=CC=C5NC=C(C)C5=C4
Biological Activity: ALK5-IN-79 (compound 57) is an ALK inhibitor with anticancer activity, by blocking TGF-β1/SMAD signaling pathway. ALK5-IN-79 attenuates the production of extracellular matrix (ECM) and deposition of collagen. ALK5-IN-79 exhibits adequate pharmacokinetic (PK) properties and good in vivo tolerance.
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ALK5-IN-79 | ALK5-IN-79 (compound 57) is an ALK inhibitor with anticancer activity, by blocking TGF-β1/SMAD signaling pathway. ALK5-IN-79 attenuates the production of extracellular matrix (ECM) and deposition of collagen. ALK5-IN-79 exhibits adequate pharmacokinetic (PK) properties and good in vivo tolerance. | |||||||||||||||||||||
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