2729981-17-1
2729981-17-1
Chemical Structure
LONP1-IN-2
- CAS No.: 2729981-17-1
- Formula:C16H27BN4O4
- Molecular Weight:350.22
IUPAC Name: ((R)-3-methyl-1-((R)-2-(pyrazine-2-carboxamido)hexanamido)butyl)boronic acid
InChIKey: UYJROBYUUYPCNR-OCCSQVGLSA-N
SMILES: CC(C)C[C@@H](B(O)O)NC([C@@H](CCCC)NC(C1=NC=CN=C1)=O)=O
Biological Activity: LONP1-IN-2 (Compound 9e) is a potent and selective LONP1 inhibitor with an IC50 value of 0.093 μM. LONP1-IN-2 can be used in research of cancer[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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LONP1-IN-2 | 99.43% | LONP1-IN-2 (Compound 9e) is a potent and selective LONP1 inhibitor with an IC50 value of 0.093 μM. LONP1-IN-2 can be used in research of cancer. | ||||||||||||||||||||
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References
- [1]. Kingsley LJ, et, al. Structure-Based Design of Selective LONP1 Inhibitors for Probing In Vitro Biology. J Med Chem. 2021 Apr 22;64(8):4857-4869. [Content Brief]
- [2]. You H, et al. Epstein-Barr virus-driven cardiolipin synthesis sustains metabolic remodeling during B cell transformation. Sci Adv. 2025 Jan 31;11(5):eadr8837. [Content Brief]
