2730023-28-4
Chemical Structure
gGlu-2OMe SiR600
- CAS No.: 2730023-28-4
- Formula:C29H30F3N3O6Si
- Molecular Weight:601.65
InChIKey: QBZMYBOZQKZHDW-BOXHHOBZSA-N
SMILES: COC1=C(C=CC=C1)C2=C3C=CC(C=C3[Si](C)(C4=CC(NC(CC[C@@H](C(O)=O)N)=O)=CC=C42)C)=N.FC(F)(F)C(O)=O
Biological Activity: gGlu-2OMe SiR600 is a γ-glutamyl transpeptidase (GGT) responsive fluorescent probe. gGlu-2OMe SiR600 can be converted into a highly fluorescent molecule via reaction with GGT, and its initial fluorescence is quenched through a photoinduced electron transfer (PeT) mechanism. gGlu-2OMe SiR600 exhibits fluorescence activation in malignant breast cancer and benign breast fibroadenoma tissues, enabling lesion visualization. gGlu-2OMe SiR600 can be used for research related to breast cancer and fibroadenoma[1].
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gGlu-2OMe SiR600 | gGlu-2OMe SiR600 is a γ-glutamyl transpeptidase (GGT) responsive fluorescent probe. gGlu-2OMe SiR600 can be converted into a highly fluorescent molecule via reaction with GGT, and its initial fluorescence is quenched through a photoinduced electron transfer (PeT) mechanism. gGlu-2OMe SiR600 exhibits fluorescence activation in malignant breast cancer and benign breast fibroadenoma tissues, enabling lesion visualization. gGlu-2OMe SiR600 can be used for research related to breast cancer and fibroadenoma. | |||||||||||||||||||||
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Keywords
