2740557-24-6
Chemical Structure
Nimucitinib
- CAS No.: 2740557-24-6
- Formula:C25H26F2N6O2
- Molecular Weight:480.51
IUPAC Name: (S)-2-hydroxy-6-((4-(2-(2-hydroxyethyl)nicotinoyl)morpholin-3-yl)methoxy)benzaldehyde
InChIKey: FDQSOYXLRVBMGA-INIZCTEOSA-N
SMILES: FC1=CC(F)=CC(CNC2=CC(NC3=CC(NC([C@H]4CCCNC4)=O)=CC=C3)=NC=C2C(N)=O)=C1
Biological Activity: Nimucitinib is a selective JAK inhibitor with potent tear secretion-promoting activity. Nimucitinib downregulates relevant signal transduction pathways by inhibiting the catalytic activity of JAK family tyrosine kinases. Nimucitinib promotes tear secretion in rabbits and inhibits corneal injury in rats. Nimucitinib can be used in dry eye-related research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Nimucitinib | 99.27% | Nimucitinib is a selective JAK inhibitor with potent tear secretion-promoting activity. Nimucitinib downregulates relevant signal transduction pathways by inhibiting the catalytic activity of JAK family tyrosine kinases. Nimucitinib promotes tear secretion in rabbits and inhibits corneal injury in rats. Nimucitinib can be used in dry eye-related research. | ||||||||||||||||||||
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Keywords
