2749562-63-6

EGFR-IN-25 Chemical Structure
2749562-63-6

Chemical Structure

EGFR-IN-25

  • CAS No.: 2749562-63-6
  • Formula:C34H43N9O2
  • Molecular Weight:609.76

IUPAC Name: 6-(1H-indol-4-yl)-3-((4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)-5-((tetrahydro-2H-pyran-4-yl)amino)pyrazine-2-carboxamide

InChIKey: ZNERTSDRRJRWIJ-UHFFFAOYSA-N

SMILES: O=C(C1=NC(C2=CC=CC3=C2C=CN3)=C(NC4CCOCC4)N=C1NC5=CC=C(N6CCC(N7CCN(C)CC7)CC6)C=C5)N

Biological Activity: EGFR-IN-25 is a potent EGFR inhibitor with IC50s of 9 nM and 60 nM for BaF3 cells (EGFR DEL19/T790M/C797S) and A431 cells (WT), respectively[1].

Cat. No. Product Name Purity Description Pricing
HY-142517 		EGFR-IN-25 EGFR-IN-25 is a potent EGFR inhibitor with IC50s of 9 nM and 60 nM for BaF3 cells (EGFR DEL19/T790M/C797S) and A431 cells (WT), respectively.
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