2749799-73-1
2749799-73-1
Chemical Structure
Disulfiram impurity 1-d10
- CAS No.: 2749799-73-1
- Formula:C6H3D10NS2
- Molecular Weight:173.37
IUPAC Name: methyl bis(ethyl-d5)carbamodithioate
InChIKey: JYRXPFCUABYLPD-IZUSZFKNSA-N
SMILES: S=C(SC)N(C([2H])([2H])C([2H])([2H])[2H])C([2H])([2H])C([2H])([2H])[2H]
Biological Activity: Disulfiram impurity 1-d10 is the deuterium labeled Disulfiram impurity 1[1].
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Disulfiram impurity 1-d10 | Disulfiram impurity 1-d10 is the deuterium labeled Disulfiram impurity 1. | |||||||||||||||||||||
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Methyl diethyldithiocarbamate-d3 | 99.95% | Methyl diethyldithiocarbamate-d3 is the deuterium labeled Methyl diethyldithiocarbamate. | ||||||||||||||||||||
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S-Methyl-N,N-diethylthiolcarbamate | 99.77% | S-Methyl-N,N-diethylthiolcarbamate (DETC-Me; DDTC-Me) is the active metabolite of the aldehyde dehydrogenase inhibitor disulfiram (HY-B0240). It is produced by the methylation of the disulfiram metabolite diethyldithiocarbamate in mouse liver microsomes. S-Methyl-N,N-diethylthiolcarbamate (DETC-Me; DDTC-Me) inhibits rat liver low Km aldehyde dehydrogenase (ALDH) (ID50=15.5 mg/kg). When administered at a dose of 20.6 mg/kg, it decreases mean arterial pressure (MAP) and increases heart rate in rats during ethanol stimulation. | ||||||||||||||||||||
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