2749855-96-5
2749855-96-5
Chemical Structure
(Rac)-Sitagliptin-d4-1 hydrochloride
Synonym(s): (Rac)-MK-0431-d4-1 hydrochloride
- CAS No.: 2749855-96-5
- Formula:C16H12D4ClF6N5O
- Molecular Weight:447.80
InChIKey: PNXSHNOORJKXDW-PBCJVBLFSA-N
SMILES: FC(F)(C1=NN=C2N1C([2H])([2H])C([2H])([2H])N(C(CC(N)CC3=C(C=C(C(F)=C3)F)F)=O)C2)F.Cl
Biological Activity: (Rac)-Sitagliptin-d4-1 hydrochloride ((Rac)-MK-0431-d4-1 hydrochloride) is the deuterium labeled (Rac)-Sitagliptin-1 hydrochloride. (Rac)-Sitagliptin is an isoform of Sitagliptin (HY-13749), which is a potent and orally active inhibitor of DPP4 with an IC50 of 19 nM in Caco-2 cell extracts[1].
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(Rac)-Sitagliptin-d4-1 hydrochloride | (Rac)-Sitagliptin-d4-1 hydrochloride ((Rac)-MK-0431-d4-1 hydrochloride) is the deuterium labeled (Rac)-Sitagliptin-1 hydrochloride. (Rac)-Sitagliptin is an isoform of Sitagliptin (HY-13749), which is a potent and orally active inhibitor of DPP4 with an IC50 of 19 nM in Caco-2 cell extracts. | |||||||||||||||||||||
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Keywords
