2750575-21-2
Chemical Structure
PDE4-IN precursor
- CAS No.: 2750575-21-2
- Formula:C32H36F2N2O10
- Molecular Weight:646.63
InChIKey: HYKKOSPPALHLPV-QASFHVGWSA-N
SMILES: OC(C)(C1=NC=C([C@@H](CC2=CN=C(C=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C(OC)=O)O)O)O)C4=CC(OC5CC5)=C(OC(F)F)C=C4)C=C1)C
Biological Activity: PDE4-IN precursor (Compound 10) is an orally active prodrug of phosphodiesterase 4 (PDE4) inhibitor. PDE4-IN precursor undergoes enzymatic hydrolysis in the colon to release the active PDE4 inhibitor, which exerts local anti-inflammatory effects on the colonic mucosa. PDE4-IN precursor is applicable to research related to ulcerative colitis, Crohn's disease, and other relevant conditions[1].
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PDE4-IN precursor | PDE4-IN precursor (Compound 10) is an orally active prodrug of phosphodiesterase 4 (PDE4) inhibitor. PDE4-IN precursor undergoes enzymatic hydrolysis in the colon to release the active PDE4 inhibitor, which exerts local anti-inflammatory effects on the colonic mucosa. PDE4-IN precursor is applicable to research related to ulcerative colitis, Crohn's disease, and other relevant conditions. | |||||||||||||||||||||
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Keywords
