2756099-59-7
2756099-59-7
Chemical Structure
Dual FAAH/sEH-IN-1
- No. CAS: 2756099-59-7
- Formula:C25H22ClN3O3S2
- Molecular Weight:512.04
IUPAC Name: N-(4-(benzo[d]thiazol-2-yl)phenyl)-1-((2-chlorophenyl)sulfonyl)piperidine-4-carboxamide
InChIKey: NVHVCPVLWHYRRB-UHFFFAOYSA-N
SMILES: O=C(C1CCN(CC1)S(=O)(C2=CC=CC=C2Cl)=O)NC3=CC=C(C=C3)C4=NC5=CC=CC=C5S4
Biological Activity: Dual FAAH/sEH-IN-1 (compound 3) is a high affinity dual sEH (soluble epoxide hydrolase) and FAAH (fatty acid amide hydrolase) inhibitor, with IC50 values of 9.6 and 7 nM, respectively. Dual FAAH/sEH-IN-1 shows antinociception against the inflammatory phase[1].
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Dual FAAH/sEH-IN-1 | Dual FAAH/sEH-IN-1 (compound 3) is a high affinity dual sEH (soluble epoxide hydrolase) and FAAH (fatty acid amide hydrolase) inhibitor, with IC50 values of 9.6 and 7 nM, respectively. Dual FAAH/sEH-IN-1 shows antinociception against the inflammatory phase. | |||||||||||||||||||||
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References
Keywords
