2757009-40-6
2757009-40-6
Chemical Structure
TYK2-IN-11
- CAS No.: 2757009-40-6
- Formula:C18H17N5O3S
- Molecular Weight:383.42
IUPAC Name: N-(4'-((6-(methylsulfonyl)pyridin-2-yl)amino)-[2,3'-bipyridin]-6'-yl)acetamide
InChIKey: SHFUHQSXZWFPTI-UHFFFAOYSA-N
SMILES: O=C(C)NC1=CC(NC2=CC=CC(S(=O)(C)=O)=N2)=C(C3=NC=CC=C3)C=N1
Biological Activity: TYK2-IN-11 (Compound 5B) is a selective Tyk-2 inhibitor with IC50s of 0.016 and 0.31 nM for TYK2-JH2 and JAK1-JH2, respectively. TYK2-IN-11 can be used for the research of inflammatory or autoimmune disease[1].
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TYK2-IN-11 | TYK2-IN-11 (Compound 5B) is a selective Tyk-2 inhibitor with IC50s of 0.016 and 0.31 nM for TYK2-JH2 and JAK1-JH2, respectively. TYK2-IN-11 can be used for the research of inflammatory or autoimmune disease. | |||||||||||||||||||||
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