2757045-58-0
2757045-58-0
Chemical Structure
(S,R,S)-AHPC-PEG2-NHS ester
- CAS No.: 2757045-58-0
- Formula:C34H45N5O10S
- Molecular Weight:715.81
InChIKey: YXXKRQYXORRNQO-HVFKJYJOSA-N
SMILES: O=C(CCC1=O)N1OC(CCOCCOCCC(NC(C(C)(C)C)C(N2[C@@H](C[C@H](C2)O)C(NCC3=CC=C(C4=C(C)N=CS4)C=C3)=O)=O)=O)=O
Biological Activity: (S, R, S)-AHPC-PEG2-NHS ester is a synthetic PROTAC linker that incorporatess an E3 ligase ligand with a PEG linker to empower PROTAC medicine chemistry. NHS ester is reactive with amine moiety. The hydrophilic PEG spacer increases its aqueous solubility.
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(S,R,S)-AHPC-PEG2-NHS ester | (S, R, S)-AHPC-PEG2-NHS ester is a synthetic PROTAC linker that incorporatess an E3 ligase ligand with a PEG linker to empower PROTAC medicine chemistry. NHS ester is reactive with amine moiety. The hydrophilic PEG spacer increases its aqueous solubility. | |||||||||||||||||||||
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Keywords
