2757548-54-0
Chemical Structure
EGFR-IN-24
- CAS No.: 2757548-54-0
- Formula:C30H35FN6O3
- Molecular Weight:546.64
IUPAC Name: tert-butyl (2S,6S)-4-benzyl-2,6-dimethylpiperazine-1-carboxylate
InChIKey: RBKVODXBOOCADL-UHFFFAOYSA-N
SMILES: COC1=C(C=NC=C1)C2=NC(C)=CC(C(NC3=NC4=CC(C5CCN(CC5)C)=CC=C4N3CC(C)(O)C)=O)=C2F
Biological Activity: EGFR-IN-24 is a selective EGFR triple mutant inhibitor with >300 nM IC50 against human EGFRdel19/T790M/C797S, EGFRL858R/T790M/C797S, and EGFRWT. EGFR-IN-24 can be used for the research of non-small cell lung cancer[1].
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EGFR-IN-24 | 98.71% | EGFR-IN-24 is a selective EGFR triple mutant inhibitor with >300 nM IC50 against human EGFRdel19/T790M/C797S, EGFRL858R/T790M/C797S, and EGFRWT. EGFR-IN-24 can be used for the research of non-small cell lung cancer. | ||||||||||||||||||||
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Keywords