2758090-62-7
2758090-62-7
Chemical Structure
LLK203
- CAS No.: 2758090-62-7
- Formula:C28H23N3O4S3
- Molecular Weight:561.69
InChIKey: JBZWMDFNFBLUSS-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(OC)C=C1NS(=O)(C2=CC=C(C3=CC=C(C)S3)C=C2)=O)NC4=NC(C5=CC=CC=C5)=CS4
Biological Activity: LLK203 is a potent USP2/USP8 dual-target inhibitor with IC50s of 0.89 μM and 0.52 μM, respectively. LLK203 leads a degradation of ERα and induces apoptosis of breast cancer MCF-7 cells. LLK203 demonstrates antitumor activities against the 4T1 tumor mice model[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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LLK203 | 98.58% | LLK203 is a potent USP2/USP8 dual-target inhibitor with IC50s of 0.89 μM and 0.52 μM, respectively. LLK203 leads a degradation of ERα and induces apoptosis of breast cancer MCF-7 cells. LLK203 demonstrates antitumor activities against the 4T1 tumor mice model. | ||||||||||||||||||||
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References
Keywords
