2764833-47-6
Chemical Structure
KTC1101
- CAS No.: 2764833-47-6
- Formula:C21H26F2N8O3
- Molecular Weight:476.48
InChIKey: YHGMSNKRMDPXAJ-UHFFFAOYSA-N
SMILES: FC(F)C1=NC2=C(OC)C=C(N)C=C2N1C3=NC(N4CCOCCC4)=NC(N5CCOCC5)=N3
Biological Activity: KTC1101 is an orally active pan-PI3K inhibitor. KTC1101 can inhibit the PI3K signaling pathway, reduce downstream AKT and mTOR phosphorylation, and reduces the expression of Ki67. The anti-tumor effect of KTC1101 has a dual mechanism of action: directly inhibiting tumor cell growth and dynamically enhancing immune response[1].
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KTC1101 | 98.09% | KTC1101 is an orally active pan-PI3K inhibitor. KTC1101 can inhibit the PI3K signaling pathway, reduce downstream AKT and mTOR phosphorylation, and reduces the expression of Ki67. The anti-tumor effect of KTC1101 has a dual mechanism of action: directly inhibiting tumor cell growth and dynamically enhancing immune response. | ||||||||||||||||||||
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Keywords