2770246-11-0
Chemical Structure
HSD17B13-IN-43
- CAS. Nr.: 2770246-11-0
- Formula:C23H14Cl2F3N3O3
- Molecular Weight:508.28
InChIKey: AZLYYNIXTDGFFV-UHFFFAOYSA-N
SMILES: O=C1C2=C(NC(C3=CC(Cl)=C(O)C(Cl)=C3)=O)C=CC=C2N=CN1CC4=CC=CC(C(F)(F)F)=C4
Biological Activity: HSD17B13-IN-43 is a selective inhibitor of HSD17B13 that competitively blocks the activity of this enzyme. HSD17B13-IN-43 exhibits an IC50 ≤ 0.1 µM in in vitro assays. HSD17B13-IN-43 can be used in studies of non-alcoholic steatohepatitis, fatty liver disease and hepatic fibrosis[1].
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HSD17B13-IN-43 | 99.68% | HSD17B13-IN-43 is a selective inhibitor of HSD17B13 that competitively blocks the activity of this enzyme. HSD17B13-IN-43 exhibits an IC50 ≤ 0.1 µM in in vitro assays. HSD17B13-IN-43 can be used in studies of non-alcoholic steatohepatitis, fatty liver disease and hepatic fibrosis. | ||||||||||||||||||||
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Keywords