2785323-62-6

PROTAC-O4I2 Chemical Structure
2785323-62-6

Chemical Structure

PROTAC-O4I2

  • CAS No.: 2785323-62-6
  • Formula:C29H29ClN6O5S
  • Molecular Weight:609.10

IUPAC Name: 2-((4-chlorophenyl)amino)-N-(6-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)hexyl)thiazole-4-carboxamide

InChIKey: UWYLVQJEOCYCEW-UHFFFAOYSA-N

SMILES: O=C(NCCCCCCNC1=CC=CC2=C1C(N(C2=O)C3CCC(NC3=O)=O)=O)C4=CSC(NC5=CC=C(C=C5)Cl)=N4

Biological Activity: PROTAC-O4I2 is a PROTAC targets splicing factor 3B1 (SF3B1). PROTAC-O4I2 induces FLAG-SF3B1 degradation with an IC50 value of 0.244 μM in K562 cells. PROTAC-O4I2 also induces cellular apoptosis in K562 WT cells[1].

Cat. No. Product Name Purity Description Pricing
HY-141881 		PROTAC-O4I2 99.56% PROTAC-O4I2 is a PROTAC targets splicing factor 3B1 (SF3B1). PROTAC-O4I2 induces FLAG-SF3B1 degradation with an IC50 value of 0.244 μM in K562 cells. PROTAC-O4I2 also induces cellular apoptosis in K562 WT cells.
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