2785430-84-2
Chemical Structure
ALK5-IN-28
- CAS No.: 2785430-84-2
- Formula:C25H27N7
- Molecular Weight:425.53
IUPAC Name: 2-(3-fluoro-2-isopropylphenyl)-9-(4-(1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl)benzyl)-7,9-dihydro-8H-purin-8-one
InChIKey: UFQRQSWJIOMAPJ-UHFFFAOYSA-N
SMILES: CC1=CC=CC2=C(NC3=NC(NC4=CC=C(CC5CCNCC5)C=C4)=NC=C3)C=NN=C12
Biological Activity: ALK5-IN-28 (Compound Ex-05) is a selective ALK-5 inhibitor (IC50 ≤ 10 nM) that inhibits TGF-β-induced SMAD signaling. ALK5-IN-28 has the potential to inhibit tumor growth in vivo. ALK5-IN-28 can be used in the research of proliferative diseases such as cancer[1][2].
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ALK5-IN-28 | ALK5-IN-28 (Compound Ex-05) is a selective ALK-5 inhibitor (IC50 ≤ 10 nM) that inhibits TGF-β-induced SMAD signaling. ALK5-IN-28 has the potential to inhibit tumor growth in vivo. ALK5-IN-28 can be used in the research of proliferative diseases such as cancer. | |||||||||||||||||||||
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Keywords
