2792202-91-4
2792202-91-4
Chemical Structure
MrgprX2-IN-1
- CAS No.: 2792202-91-4
- Formula:C22H21F3N6O
- Molecular Weight:442.44
SMILES: O=C(N[C@@H]1CC[C@H](NC2=CC=CC3=NC(C(F)(F)F)=CN23)CC1)C4=C(NN=C5)C5=CC=C4
Biological Activity: MrgprX2-IN-1 (Compound 2-10) is a selective Mas-related G-protein coupled receptor X2 (MRGPRX2) antagonist. MrgprX2-IN-1 blocks IgE-independent immune responses by inhibiting MRGPRX2-mediated mast cell degranulation and release of inflammatory mediators. MrgprX2-IN-1 is promising for research of pseudo-allergic reactions, chronic pruritus, and inflammatory diseases[1].
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MrgprX2-IN-1 | MrgprX2-IN-1 (Compound 2-10) is a selective Mas-related G-protein coupled receptor X2 (MRGPRX2) antagonist. MrgprX2-IN-1 blocks IgE-independent immune responses by inhibiting MRGPRX2-mediated mast cell degranulation and release of inflammatory mediators. MrgprX2-IN-1 is promising for research of pseudo-allergic reactions, chronic pruritus, and inflammatory diseases. | |||||||||||||||||||||
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References
Keywords
