2798953-78-1
Chemical Structure
SCAL-266
- CAS No.: 2798953-78-1
- Formula:C27H28F3N5O2
- Molecular Weight:511.54
InChIKey: ODXBKEDGMKYXEZ-UHFFFAOYSA-N
SMILES: O=C(C1=NN(CC2=CC=CC(N3CCN(C(C4CC4)=O)CC3)=C2)C(C)=C1)NC5=CC=C(C(F)(F)F)C=C5
Biological Activity: SCAL-266 is a potent mitochondrial complex I (CI) inhibitor with IC50 of 0.83 μM. SCAL-266 blocks mitochondrial function, inhibits OCR, induces ROS production, and reduces MMP. SCAL-266 displays a considerable antiproliferation effect against oxidative phosphorylation (OXPHOS)-dependent cancer cells[1].
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SCAL-266 | SCAL-266 is a potent mitochondrial complex I (CI) inhibitor with IC50 of 0.83 μM. SCAL-266 blocks mitochondrial function, inhibits OCR, induces ROS production, and reduces MMP. SCAL-266 displays a considerable antiproliferation effect against oxidative phosphorylation (OXPHOS)-dependent cancer cells. | |||||||||||||||||||||
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Keywords