28034-72-2
28034-72-2
Chemical Structure
4’,5’-Didehydro-5’-deoxy thymidine
- CAS No.: 28034-72-2
- Formula:C10H12N2O4
- Molecular Weight:224.21
IUPAC Name: 1-((2R,4S)-4-hydroxy-5-methylenetetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
InChIKey: GHLYSDYPUZQXIN-JGVFFNPUSA-N
SMILES: O=C(C(C)=C1)NC(N1[C@@H](C[C@@H]2O)OC2=C)=O
Biological Activity: 4’,5’-Didehydro-5’-deoxy thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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4’,5’-Didehydro-5’-deoxy thymidine | 4’,5’-Didehydro-5’-deoxy thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
Keywords
