2839639-94-8
2839639-94-8
Chemical Structure
STING modulator-3
- CAS. Nr.: 2839639-94-8
- Formula:C18H17N9O
- Molecular Weight:375.39
IUPAC Name: 4-(4-(1-(cyanomethyl)-3-methyl-1H-pyrazol-5-yl)-1-methyl-1H-imidazol-2-yl)-1-methyl-1H-pyrazolo[4,3-c]pyridine-6-carboxamide
InChIKey: FABUXAHVXJIHGI-UHFFFAOYSA-N
SMILES: N#CCN1N=C(C)C=C1C2=CN(C)C(C3=NC(C(N)=O)=CC4=C3C=NN4C)=N2
Biological Activity: STING modulator-3 is a STING inhibitor. STING modulator-3 inhibits R232 STING with an Ki value of 43.1 nM in scintillation proximity assay. STING modulator-3 has no effect on IRF-3 activation or TNF-β induction in THP-1 cells[1].
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STING modulator-3 | STING modulator-3 is a STING inhibitor. STING modulator-3 inhibits R232 STING with an Ki value of 43.1 nM in scintillation proximity assay. STING modulator-3 has no effect on IRF-3 activation or TNF-β induction in THP-1 cells. | |||||||||||||||||||||
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