2850370-28-2
2850370-28-2
Chemical Structure
Microtubule destabilizing agent-1
- CAS No.: 2850370-28-2
- Formula:C22H26N4O4
- Molecular Weight:410.47
IUPAC Name: N-hydroxy-2-(2-methoxy-5-(methyl(2-methylquinazolin-4-yl)amino)phenoxy)-3-methylbutanamide
InChIKey: ZTYHIBVAHSWEEK-UHFFFAOYSA-N
SMILES: CN(C1=NC(C)=NC2=CC=CC=C12)C3=CC(OC(C(C)C)C(NO)=O)=C(OC)C=C3
Biological Activity: Microtubule destabilizing agent-1 (Compound 12b) acts as a microtubule destabilizing agent (MDA) based on hydroxamic acid, could serve as a potential MDA for further investigation. Microtubule destabilizing agent-1 shows favorable metabolism stability, high bioavailability, and potent antitumor activity[1].
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Microtubule destabilizing agent-1 | Microtubule destabilizing agent-1 (Compound 12b) acts as a microtubule destabilizing agent (MDA) based on hydroxamic acid, could serve as a potential MDA for further investigation. Microtubule destabilizing agent-1 shows favorable metabolism stability, high bioavailability, and potent antitumor activity. | |||||||||||||||||||||
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