2868312-73-4
2868312-73-4
Chemical Structure
DC-LC3in-D5
- CAS No.: 2868312-73-4
- Formula:C19H22Cl2N2O3
- Molecular Weight:397.30
IUPAC Name: 5-(2,3-dichlorophenyl)-2-(((2-morpholinoethyl)amino)methylene)cyclohexane-1,3-dione
InChIKey: QWRGQCLNVZLPJO-QINSGFPZSA-N
SMILES: O=C1/C(C(CC(C2=C(Cl)C(Cl)=CC=C2)C1)=O)=C/NCCN3CCOCC3
Biological Activity: DC-LC3in-D5 acts as an autophagy inhibitor by attenuating LC3B lipidation. DC-LC3in-D5 binds with LC3B. DC-LC3in-D5 disrupts the LC3B-LBP2 interaction with an IC50 of 200 nM. DC-LC3in-D5 may contribute to anti-HCV or combination researchs in cancer through inhibiting autophagy[1].
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DC-LC3in-D5 | 98.62% | DC-LC3in-D5 acts as an autophagy inhibitor by attenuating LC3B lipidation. DC-LC3in-D5 binds with LC3B. DC-LC3in-D5 disrupts the LC3B-LBP2 interaction with an IC50 of 200 nM. DC-LC3in-D5 may contribute to anti-HCV or combination researchs in cancer through inhibiting autophagy. | ||||||||||||||||||||
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