288079-93-6
Chemical Structure
BMS-344577
- CAS No.: 288079-93-6
- Formula:C31H37N7O5
- Molecular Weight:587.67
IUPAC Name: (S,E)-N2,N2-dimethyl-N5-(N'-(2-methylbenzofuran-5-yl)-N-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)azepan-3-yl)carbamimidoyl)pyridine-2,5-dicarboxamide
InChIKey: YLSKCQOVDOZHTQ-VWLOTQADSA-N
SMILES: O=C(N(CCCC1)CC(N2CCCC2)=O)[C@H]1N/C(NC(C3=CN=C(C(N(C)C)=O)C=C3)=O)=N\C4=CC=C(OC(C)=C5)C5=C4
Biological Activity: BMS-344577 (Compound 22) is a potent and orally active factor Xa inhibitor (IC50 = 4 nM, EC2xPT = 7 μM). BMS-344577 shows potent CYP3A4 inhibition activity (IC50 = 0.3 μM). BMS-344577 can be used for the research of cardiovascular disease[1].
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BMS-344577 | BMS-344577 (Compound 22) is a potent and orally active factor Xa inhibitor (IC50 = 4 nM, EC2xPT = 7 μM). BMS-344577 shows potent CYP3A4 inhibition activity (IC50 = 0.3 μM). BMS-344577 can be used for the research of cardiovascular disease. | |||||||||||||||||||||
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Keywords
