2885227-09-6
2885227-09-6
Chemical Structure
RIPK2-IN-5
- CAS No.: 2885227-09-6
- Formula:C21H14N4S
- Molecular Weight:354.43
InChIKey: DDRVRFLMLJHXSY-UHFFFAOYSA-N
SMILES: C12=CC(NC3=CC=NC4=CC=C(C5=CC=NC=C5)C=C34)=CC=C1SC=N2
Biological Activity: RIPK2-IN-5 (compound 14) is a high affinity and excellent selectivity RIPK2 inhibitor with an IC50 value of 5.1nM. RIPK2-IN-5 has cellular anti-inflammatory effect and can reduce the secretion of MDP-induced TNF-α with a dose-dependent manner. RIPK2-IN-5 shows moderate stability in human liver microsome. RIPK2-IN-5 can be used for the research of immune diseases[1].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
RIPK2-IN-5 | 99.73% | RIPK2-IN-5 (compound 14) is a high affinity and excellent selectivity RIPK2 inhibitor with an IC50 value of 5.1nM. RIPK2-IN-5 has cellular anti-inflammatory effect and can reduce the secretion of MDP-induced TNF-α with a dose-dependent manner. RIPK2-IN-5 shows moderate stability in human liver microsome. RIPK2-IN-5 can be used for the research of immune diseases. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
