2890696-59-8
2890696-59-8
Chemical Structure
Binimetinib-d3
Synonym(s): MEK162-d3; ARRY-162-d3; ARRY-438162-d3
- CAS No.: 2890696-59-8
- Formula:C17H12D3BrF2N4O3
- Molecular Weight:444.25
InChIKey: ACWZRVQXLIRSDF-FIBGUPNXSA-N
SMILES: O=C(C1=C(NC2=CC=C(Br)C=C2F)C(F)=C3C(N(C([2H])([2H])[2H])C=N3)=C1)NOCCO
Biological Activity: Binimetinib-d3 (MEK162-d3) is deuterium labeled Binimetinib. Binimetinib (MEK162) is an oral and selective MEK1/2 inhibitor. Binimetinib (MEK162) inhibits MEK with an IC50 of 12 nM[1].
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Binimetinib-d3 | Binimetinib-d3 (MEK162-d3) is deuterium labeled Binimetinib. Binimetinib (MEK162) is an oral and selective MEK1/2 inhibitor. Binimetinib (MEK162) inhibits MEK with an IC50 of 12 nM. | |||||||||||||||||||||
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Binimetinib (Standard) | ≥98% | Binimetinib (Standard) is the analytical standard of Binimetinib. This product is intended for research and analytical applications. Binimetinib (MEK162) is an oral and selective MEK1/2 inhibitor. Binimetinib (MEK162) inhibits MEK with an IC50 of 12 nM. | ||||||||||||||||||||
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Binimetinib-d4 | Binimetinib-d4 (MEK162-d4) is deuterium labeled Binimetinib. Binimetinib (MEK162) is an oral and selective MEK1/2 inhibitor. Binimetinib (MEK162) inhibits MEK with an IC50 of 12 nM. | |||||||||||||||||||||
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Binimetinib | 99.92% | Binimetinib (MEK162) is an oral and selective MEK1/2 inhibitor. Binimetinib (MEK162) inhibits MEK with an IC50 of 12 nM. | ||||||||||||||||||||
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References
