289479-07-8
289479-07-8
Chemical Structure
AAE871
- CAS No.: 289479-07-8
- Formula:C24H34N8O2S
- Molecular Weight:498.64
IUPAC Name: N2-((1r,4r)-4-aminocyclohexyl)-9-ethyl-N6-(4-(piperidin-1-ylsulfonyl)phenyl)-9H-purine-2,6-diamine
InChIKey: IUUNTNJCKSXDOW-UAPYVXQJSA-N
SMILES: O=S(C1=CC=C(NC2=C3N=CN(CC)C3=NC(N[C@H]4CC[C@H](N)CC4)=N2)C=C1)(N5CCCCC5)=O
Biological Activity: AAE871 is a potent type I FLT3 inhibitor with an IC50 value of 0.034 µM. AE871 has the potential for the research of acute myeloid leukemia (AML) [1].
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AAE871 | AAE871 is a potent type I FLT3 inhibitor with an IC50 value of 0.034 µM. AE871 has the potential for the research of acute myeloid leukemia (AML) . | |||||||||||||||||||||
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References
Keywords
