292135-78-5
292135-78-5
Chemical Structure
Roflumilast N-oxide
- CAS No.: 292135-78-5
- Formula:C17H14Cl2F2N2O4
- Molecular Weight:419.21
IUPAC Name: 3,5-dichloro-4-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzamido)pyridine 1-oxide
InChIKey: PCGSQNPMMSALEJ-UHFFFAOYSA-N
SMILES: O=C(NC1=C(Cl)C=N(C=C1Cl)=O)C2=CC=C(OC(F)F)C(OCC3CC3)=C2
Biological Activity: Roflumilast N-oxide is a PDE type 4 inhibitor.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Roflumilast N-oxide | 99.52% | Roflumilast N-oxide is a PDE type 4 inhibitor. | ||||||||||||||||||||
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Roflumilast N-oxide (Standard) | 99.24% | Roflumilast N-oxide (Standard) is the analytical standard of Roflumilast N-oxide. This product is intended for research and analytical applications. Roflumilast N-oxide is a PDE type 4 inhibitor. | ||||||||||||||||||||
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Roflumilast-d4 N-Oxide | 98.13% | Roflumilast-d4 N-Oxide is the deuterium labeled Roflumilast. Roflumilast is a selective PDE4 inhibitor with IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDEA4, PDEB1, and PDEB2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells. | ||||||||||||||||||||
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