2925330-18-1
2925330-18-1
Chemical Structure
MAT2A-IN-22
- CAS No.: 2925330-18-1
- Formula:C18H11D3F3N3O
- Molecular Weight:348.34
InChIKey: QORHMXRPXOGKGZ-DBHFXHLNSA-N
SMILES: O=C1[C@]2(C3=CC(C(F)(F)F)=CC=C3C(NC([2H])([2H])[2H])=N1)C4=CC=CN=C4CC2
Biological Activity: MAT2A-IN-22 (Compound 29-1) is a BBB-penetrable and orally active MAT2A inhibitor with an IC50 of 4 nM. MAT2A-IN-22 shows selectivity and inhibitory activity against MTAP-deficient cancer cell lines. MAT2A-IN-22 has anti-tumor effects[1].
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MAT2A-IN-22 | MAT2A-IN-22 (Compound 29-1) is a BBB-penetrable and orally active MAT2A inhibitor with an IC50 of 4 nM. MAT2A-IN-22 shows selectivity and inhibitory activity against MTAP-deficient cancer cell lines. MAT2A-IN-22 has anti-tumor effects. | |||||||||||||||||||||
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