2932459-63-5
2932459-63-5
Chemical Structure
LRH-1 antagonist-1 dihydrochloride
- CAS 番号: 2932459-63-5
- Formula:C21H30Cl2N6
- Molecular Weight:437.41
InChIKey: PQBXKDUKUFSVIF-UHFFFAOYSA-N
SMILES: CN(C)CCN(C=C1)N=C1C2=CC(C3=C(C)C(C)=NC(N(C)C)=N3)=CC=C2.Cl.Cl
Biological Activity: LRH-1 antagonist-1 (Compound 3d2) dihydrochloride is a LRH-1 antagonist with a Kd of 1.8 μM. LRH-1 antagonist-1 dihydrochloride inhibits the transcriptional activity of LRH-1 and reduces the expression of G0S2. LRH-1 antagonist-1 dihydrochloride inhibits the proliferation of LRH-1-positive cancer cells. LRH-1 antagonist-1 dihydrochloride can be used for research on pancreatic cancer, colon cancer and breast cancer[1].
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LRH-1 antagonist-1 dihydrochloride | LRH-1 antagonist-1 (Compound 3d2) dihydrochloride is a LRH-1 antagonist with a Kd of 1.8 μM. LRH-1 antagonist-1 dihydrochloride inhibits the transcriptional activity of LRH-1 and reduces the expression of G0S2. LRH-1 antagonist-1 dihydrochloride inhibits the proliferation of LRH-1-positive cancer cells. LRH-1 antagonist-1 dihydrochloride can be used for research on pancreatic cancer, colon cancer and breast cancer. | |||||||||||||||||||||
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