2941386-60-1
2941386-60-1
Chemical Structure
PBA-1105b
- CAS No.: 2941386-60-1
- Formula:C47H64N2O10
- Molecular Weight:817.02
InChIKey: XYFRMJRHIZEQPA-UHFFFAOYSA-N
SMILES: O=C(CCCC1=CC=CC=C1)NCCOCCOCCOCCOCCOCCOCCOCCNCC2=CC(OCC3=CC=CC=C3)=C(OCC4=CC=CC=C4)C=C2
Biological Activity: PBA-1105b is an autophagy-targeting chimera (AUTOTAC) that induces p62 self-oligomerization. PBA-1105b binds to the ZZ domain of p62, inducing conformational activation and self-oligomerization for autophagy targeting. PBA-1105b is used in research on neurodegenerative diseases[1].
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PBA-1105b | 98.01% | PBA-1105b is an autophagy-targeting chimera (AUTOTAC) that induces p62 self-oligomerization. PBA-1105b binds to the ZZ domain of p62, inducing conformational activation and self-oligomerization for autophagy targeting. PBA-1105b is used in research on neurodegenerative diseases. | ||||||||||||||||||||
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