2948309-57-5
2948309-57-5
Chemical Structure
PptT-IN-4
- CAS No.: 2948309-57-5
- Formula:C17H23N3
- Molecular Weight:269.38
InChIKey: INMRKBDZTKEPHM-UHFFFAOYSA-N
SMILES: CCC1=C(NC2=CC=CC(NCC)=N2)C(CC)=CC=C1
Biological Activity: PptT-IN-4 (Compound 3a) is a PptT inhibitor (IC50: 0.71 μM). PptT-IN-4 inhibits Mtb H37Rv with a MIC value of 42 μM. PptT-IN-4 also inhibits hERG, hCav1.2, and hNav1.5 channels with IC50s of 11 μM, 8.1 μM, 6.9 μM respectively[1].
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PptT-IN-4 | PptT-IN-4 (Compound 3a) is a PptT inhibitor (IC50: 0.71 μM). PptT-IN-4 inhibits Mtb H37Rv with a MIC value of 42 μM. PptT-IN-4 also inhibits hERG, hCav1.2, and hNav1.5 channels with IC50s of 11 μM, 8.1 μM, 6.9 μM respectively. | |||||||||||||||||||||
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