2951854-02-5
Chemical Structure
SHP2-IN-13
- CAS No.: 2951854-02-5
- Formula:C16H21N7O
- Molecular Weight:327.38
IUPAC Name: 4-amino-2-(4-amino-4-methylpiperidin-1-yl)-N-(pyridin-3-yl)pyrimidine-5-carboxamide
InChIKey: HFSPLSHISPIUQQ-UHFFFAOYSA-N
SMILES: CC1(CCN(CC1)C2=NC=C(C(N)=N2)C(NC3=CN=CC=C3)=O)N
Biological Activity: SHP2-IN-13 is a highly selective and orally active SHP2 “tunnel site” allosteric inhibitor with an IC50 of 83.0 nM. SHP2-IN-13 has the potential for cancers bearing RTK oncogenic drivers and SHP2-related diseases research.
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SHP2-IN-13 | 99.41% | SHP2-IN-13 is a highly selective and orally active SHP2 “tunnel site” allosteric inhibitor with an IC50 of 83.0 nM. SHP2-IN-13 has the potential for cancers bearing RTK oncogenic drivers and SHP2-related diseases research. | ||||||||||||||||||||
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Keywords