2961381-94-0
2961381-94-0
Chemical Structure
Antitrypanosomal agent 15
- CAS No.: 2961381-94-0
- Formula:C21H19FN4O4
- Molecular Weight:410.40
InChIKey: GGRYBCDDGWXURQ-UHFFFAOYSA-N
SMILES: CNC(C1=C(F)C=CC(NC(C2=NN(C(C=C2)=O)CC3=CC=C(OC)C=C3)=O)=C1)=O
Biological Activity: Antitrypanosomal agent 15 (compound 26) is an orally active, brain-penetrant, selective inhibitor against Trypanosoma cruzi proteasome, with an pIC50 of 7.4 and <4 for T. cruzi and human proteasome, respectively. Antitrypanosomal agent 15 has favorable ADME properties and can be used for Chagas disease study[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Antitrypanosomal agent 15 | Antitrypanosomal agent 15 (compound 26) is an orally active, brain-penetrant, selective inhibitor against Trypanosoma cruzi proteasome, with an pIC50 of 7.4 and <4 for T. cruzi and human proteasome, respectively. Antitrypanosomal agent 15 has favorable ADME properties and can be used for Chagas disease study. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
