2962103-54-2
Chemical Structure
ZG-2305
- CAS No.: 2962103-54-2
- Formula:C17H11Cl2N3O5
- Molecular Weight:408.19
InChIKey: IVVBSKSURSLYFK-UHFFFAOYSA-N
SMILES: OC(CNC(C1=NC=C(C=C1O)C2=CC(C3=CC(Cl)=CC(Cl)=C3)=NO2)=O)=O
Biological Activity: ZG-2305 is a potent, orally active and selective factor inhibiting hypoxia-inducible factor (FIH) inhibitor with Ki values of 79.6, 2786 nM for FIH, PHD2, respectively. ZG-2305 increases the expression of EGLN3 gene. ZG-2305 decreases the cellular triglycerides levels and reduces lipid accumulation. ZG-2305 has the potential for the research of obesity and fatty liver disease[1].
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ZG-2305 | 98.60% | ZG-2305 is a potent, orally active and selective factor inhibiting hypoxia-inducible factor (FIH) inhibitor with Ki values of 79.6, 2786 nM for FIH, PHD2, respectively. ZG-2305 increases the expression of EGLN3 gene. ZG-2305 decreases the cellular triglycerides levels and reduces lipid accumulation. ZG-2305 has the potential for the research of obesity and fatty liver disease. | ||||||||||||||||||||
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Keywords