2982792-85-6
Chemical Structure
DYB-03
- CAS. Nr.: 2982792-85-6
- Formula:C28H33NO6
- Molecular Weight:479.56
InChIKey: QKJKOCQFEZTVJK-VMPITWQZSA-N
SMILES: COC1=CC=C(/C=C/C(C2=CC=C(OC(C)(C)C=C3)C3=C2O)=O)C=C1OCCCN4CCOCC4
Biological Activity: DYB-03 is an oral active HIF-1α/EZH2 inhibitor. DYB-03 inhibits migration, invasion, and angiogenesis of lung cancer cells and HUVECs in vitro and in vivo. DYB-03 induces apoptosis in 2-ME2- and GSK126-resistant of A549 and H460 cells[1].
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DYB-03 | 99.49% | DYB-03 is an oral active HIF-1α/EZH2 inhibitor. DYB-03 inhibits migration, invasion, and angiogenesis of lung cancer cells and HUVECs in vitro and in vivo. DYB-03 induces apoptosis in 2-ME2- and GSK126-resistant of A549 and H460 cells. | ||||||||||||||||||||
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Keywords