2992690-04-5
2992690-04-5
Chemical Structure
LSD1-IN-35
- CAS No.: 2992690-04-5
- Formula:C25H26N4O2S
- Molecular Weight:446.56
InChIKey: RNALORNFLHWMDN-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(C2=NC3=CC=CC=C3C(NC4=CC=C(C=C4)N(CC)CC)=N2)C=C1)(C)=O
Biological Activity: LSD1-IN-35 (Compound Z-1) is a selective LSD1 Inhibitor (IC50: 108 nM). LSD1-IN-35 inhibits the demethylation on H3K4me1/2. LSD1-IN-35 is an immunomodulator. LSD1-IN-35 promotes response of gastric cancer cells to T-cell killing effect by decreasing PD-L1 expression and further attenuates the PD-1/PD-L1 interaction[1].
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LSD1-IN-35 | LSD1-IN-35 (Compound Z-1) is a selective LSD1 Inhibitor (IC50: 108 nM). LSD1-IN-35 inhibits the demethylation on H3K4me1/2. LSD1-IN-35 is an immunomodulator. LSD1-IN-35 promotes response of gastric cancer cells to T-cell killing effect by decreasing PD-L1 expression and further attenuates the PD-1/PD-L1 interaction. | |||||||||||||||||||||
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References
Keywords
