300817-68-9
300817-68-9
Chemical Structure
BH3I-1
Synonym(s): BHI1
- CAS No.: 300817-68-9
- Formula:C15H14BrNO3S2
- Molecular Weight:400.31
IUPAC Name: (E)-2-(5-(4-bromobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)-3-methylbutanoic acid
InChIKey: COHIEJLWRGREHV-YRNVUSSQSA-N
SMILES: O=C(O)C(C(C)C)N(C/1=O)C(SC1=C\C2=CC=C(Br)C=C2)=S
Biological Activity: BH3I-1 is a Bcl-2 family antagonist, which inhibits the binding of the Bak BH3 peptide to Bcl-xL with a Ki of 2.4±0.2 μM in FP assay. BH3I-1 has a Kd of 5.3 μM against the p53/MDM2 pair.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BH3I-1 | 98.0% | BH3I-1 is a Bcl-2 family antagonist, which inhibits the binding of the Bak BH3 peptide to Bcl-xL with a Ki of 2.4±0.2 μM in FP assay. BH3I-1 has a Kd of 5.3 μM against the p53/MDM2 pair. | ||||||||||||||||||||
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Keywords
