3014815-06-3
3014815-06-3
Chemical Structure
BET-IN-21
- CAS No.: 3014815-06-3
- Formula:C20H20N6
- Molecular Weight:344.41
InChIKey: AGXHDPYHRCHDBA-UHFFFAOYSA-N
SMILES: CC1=NN(C(C)=C1C2=CC(C3=C4NC=NC4=NC=C3)=CN=C2)CC5CC5
Biological Activity: BET-IN-21 (compound 16) is a blood-brain barrier-permeable extra terminal domain (BET) inhibitor with the Ki of 230 nM. BET-IN-21 inhibits microglia activation and has ameliorative effects on experimental autoimmune encephalomyelitis mice[1].
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BET-IN-21 | BET-IN-21 (compound 16) is a blood-brain barrier-permeable extra terminal domain (BET) inhibitor with the Ki of 230 nM. BET-IN-21 inhibits microglia activation and has ameliorative effects on experimental autoimmune encephalomyelitis mice. | |||||||||||||||||||||
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