3018057-89-8
Chemical Structure
KRAS G12D-IN-29
- CAS No.: 3018057-89-8
- Formula:C31H33F6N7O2
- Molecular Weight:649.63
InChIKey: HLUXAQFQTFKPSI-WMHAXWKYSA-N
SMILES: FC(F)(F)C1=C(C2=NC3=C4C(N(C[C@@H]5N[C@H]6CC5)[C@@H]6[C@H](C)O3)=NC(OC[C@]78N(C[C@H](F)C8)CCC7)=NC4=C2F)C=C(N)C(F)=C1C
Biological Activity: KRAS G12D inhibitor 29 (Compound Formula (I)) is an orally active and selective KRASG12D mutant inhibitor. KRAS G12D inhibitor 29 blocks downstream signaling pathways mediated by KRASG12D, suppressing tumor cell proliferation. KRAS G12D inhibitor 29 is promising for research of KRASG12D mutation-related cancers (such as pancreatic cancer, lung cancer, colorectal cancer)[1].
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KRAS G12D-IN-29 | 99.93% | KRAS G12D inhibitor 29 (Compound Formula (I)) is an orally active and selective KRASG12D mutant inhibitor. KRAS G12D inhibitor 29 blocks downstream signaling pathways mediated by KRASG12D, suppressing tumor cell proliferation. KRAS G12D inhibitor 29 is promising for research of KRASG12D mutation-related cancers (such as pancreatic cancer, lung cancer, colorectal cancer). | ||||||||||||||||||||
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Keywords