3024909-61-0

GSPT1 degrader-10 Chemical Structure
3024909-61-0

Chemical Structure

GSPT1 degrader-10

  • CAS No.: 3024909-61-0
  • Formula:C38H38ClN7O5
  • Molecular Weight:708.21

InChIKey: RQRVDLHEZAZZNS-UHFFFAOYSA-N

SMILES: O=C1NC(C(CC1)N2C(C3=CC=C(N4CCC(CC4)CN5C(N(CCC5)C6=CC(C7=C(Cl)C8=C(NC=C8CC)N=C7)=CC=C6)=O)C=C3C2=O)=O)=O

Biological Activity: GSPT1 degrader-10 (compound A) is a cereblon-based molecular glue degrader of GSPT1 with more than 95% degradation. GSPT1 degrader-8 inhibits cell viability in HL-60 cells with an IC50 of 10 nM[1].

Cat. No. Product Name Purity Description Pricing
HY-159610 		GSPT1 degrader-10 GSPT1 degrader-10 (compound A) is a cereblon-based molecular glue degrader of GSPT1 with more than 95% degradation. GSPT1 degrader-8 inhibits cell viability in HL-60 cells with an IC50 of 10 nM.
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