3026111-73-6
3026111-73-6
Chemical Structure
TrkA-IN-3
- CAS No.: 3026111-73-6
- Formula:C24H17F3N4O3
- Molecular Weight:466.41
IUPAC Name: 5-(3-(1-methyl-1H-pyrazol-3-yl)-4-(trifluoromethyl)benzamido)-6-phenylnicotinic acid
InChIKey: MLKKBTKDOPHWET-UHFFFAOYSA-N
SMILES: CN1C=CC(C2=CC(C(NC3=CC(C(O)=O)=CN=C3C4=CC=CC=C4)=O)=CC=C2C(F)(F)F)=N1
Biological Activity: TrkA-IN-3 is a potent, subselective and allosteric TrkA inhibitor, with an IC50 of 22.4 nM. TrkA-IN-3 shows more than 8000-fold selectivity for TrkA over TrkB and TrkC. TrkA-IN-3 can be used for the research of pain[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TrkA-IN-3 | 98.01% | TrkA-IN-3 is a potent, subselective and allosteric TrkA inhibitor, with an IC50 of 22.4 nM. TrkA-IN-3 shows more than 8000-fold selectivity for TrkA over TrkB and TrkC. TrkA-IN-3 can be used for the research of pain. | ||||||||||||||||||||
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References
Keywords
