3026111-74-7
Chemical Structure
TrkA-IN-4
- CAS No.: 3026111-74-7
- Formula:C27H21F3N4O5
- Molecular Weight:538.47
IUPAC Name: acetoxymethyl 5-(3-(1-methyl-1H-pyrazol-3-yl)-4-(trifluoromethyl)benzamido)-6-phenylnicotinate
InChIKey: FMICUWJKVYFTRQ-UHFFFAOYSA-N
SMILES: CC(OCOC(C1=CN=C(C(NC(C2=CC=C(C(C3=NN(C=C3)C)=C2)C(F)(F)F)=O)=C1)C4=CC=CC=C4)=O)=O
Biological Activity: TrkA-IN-4, a potent, orally active and allosteric TrkA inhibitor, is a proagent of TrkA-IN-3 (IC50=22.4 nM, HY-151948). TrkA-IN-4 exhibits potent antinociceptive effects[1].
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TrkA-IN-4 | 98.99% | TrkA-IN-4, a potent, orally active and allosteric TrkA inhibitor, is a proagent of TrkA-IN-3 (IC50=22.4 nM, HY-151948). TrkA-IN-4 exhibits potent antinociceptive effects. | ||||||||||||||||||||
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Keywords